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Sequencing of selected phage-Abs revealed that they used different VH and VL genes with, for the majority of them, a high level of extensive hypermutations in the complementarity determining regions, indicating the diversity of the antigen-driven immune response that occurred in GT and AITP patients.
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The hypothesis states that people with high cognitive function throughout life (high IQ, high level of education, extensive literacy and complex social groups) can flexibly and efficiently draw processing power from other brain regions and thus retain general cognitive ability, despite underlying pathology [ 60].
Alpine habitats often have a high level of protection, yet extensive environmental heterogeneity and the limited dispersal ability of many endemic species makes it unclear whether PA networks provide sufficient connectivity to protect vulnerable species.
The practice of motivational interviewing requires a high level of skills and extensive training [ 49].
In almost all case control studies, a high level of brain imaging and extensive phenotyping was performed, although this was less detailed in some of the prospective studies.
These studies indicate that HeLa has a high level of aneuploidy, numerous large structural variants, extensive point mutations and extensive genomic rearrangement, especially at chromosome 8q24.21, the hotspot site HPV-18 genome integration [ 26, 27].
50 Recently, extensive and high level of multiple insecticide resistance was found in An. sinensis from the malaria-endemic areas in China.
Comparative mapping revealed that despite extensive rearrangements, a high level of conservation was detected between the coffee tree and the tomato, reinforcing the assessment of Rubiaceae and Solanaceae as "sister" plant families [ 14].
Features in common for the two lineages are: (1) a very high level of gene relocation from the mitochondrion, (2) extensive rRNA gene fragmentation and dispersal, and (3) use of non-standard initiation codons.
The main reasons were lack of local clinical input, inappropriate consideration of resources, failure to apply to a specific population, too extensive recommendations, a high level of complexity in guidelines for users, and failure to include the most recent information in guidelines.
Despite the postdocs' extensive training, expertise, and high level of responsibility, many experts believe their starting salaries are too low.
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