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Also, the lateral stiffness increased and degradation of the lateral stiffness occurred at a high level of drift.
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The results indicate appropriate and acceptable behaviour of the system even in high levels of drift.
Genome-wide comparisons of K a/K s ratios across lineages have been used as a proxy for differences in the effects of genetic drift on a genome because high levels of drift will escalate the fixation of slightly deleterious substitutions, thereby increasing the relative numbers of nonsynonymous substitutions (Daubin and Moran 2004; Kuo et al. 2009).
Thus these two models didn't appear relevant for such high level of pure drift divergence as expected by the marked difference (even for SNPs with ancestral reference allele frequency close to 0.5) between the expected distribution of within population allele frequency [24] and the distributions assumed in the models (Figure S3).
This could partly be a result of a downward selection process, where those with a high level of absence drift towards less favourable jobs with lower opportunities for discretion.
This is apparent in the plots of Ks against both Ka and K16S, in which those bacteria subject to higher levels of drift have elevated divergence at slightly deleterious sites (Ka and K16S) relative to neutral sites (Ks).
This contrasts the situation in bacteria where the higher levels of drift are associated with smaller genomes (Kuo et al. 2009) due to mutational biases that cause the removal both of nonfunctional sequences and of genes that are under reduced selective constraints due to drift.
Bacteria with lifestyles that reduce long-term effective population size (such as obligate endosymbiosis or vector-dependent transmission) and impose higher levels of drift have the most highly reduced genomes (Moran and Plague 2004; Ochman and Davalos 2006; Moran et al. 2008, 2009).
As to America, it is well known [26] that the genetic structure of Amerindian populations is characterized by high levels of genetic drift.
Closed populations with high levels of genetic drift suffer from reduction of genetic diversity.
This could lead to new adaptive pressures [ 53], or high levels of genetic drift in population bottlenecks [ 54].
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