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This high level of differential expression will cause the downstream genes to be statistically correlated.
Second, one or two genes in a group often displays a high level of differential expression.
Using a custom microarray, this analysis revealed a high level of differential expression, using relatively stringent statistical criteria.
Maltase-glucoamylase was further included because of its high level of differential expression (105-fold) between salmon louse strains.
After the genes were ordered according to increasing p-values, the genes at the top of the list yielded a high level of differential information.
Quantitative real-time PCR (qRT-PCR) was performed to confirm the expression of the 12 genes/sequences involved in the mechanisms related to neurodegenerative or reparation processes and/or had a high level of differential expression in the scrapie group compared to the controls in the oligo-DNA microarray expression analysis.
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This interpretation is consistent with the relatively high levels of differential gene expression observed for samples in these three clusters.
Formerly available methods for expression profiling usually had to apply filtering criteria like signal intensity, "Present" calls and stringent cutoffs for high levels of differential expression to avoid false-positive calls.
For G12, all four candidates demonstrated high levels of differential expression.
In contrast, our PSRP 91 gene TaqMan assay did not require genes to have high levels of differential.
One of the first attempts is a general method to search for 'active sub-networks' connecting genes with unexpectedly high levels of Differential Expression (Ideker et al., 2002).
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