Finally, quantification of Grp78high/CD138+ MM cells from patients suggested that high levels correlated with progressive disease.
Both estimates showed that the high levels correlated significantly to short DFS in the CC patient group of which the TBR values provided the best correlation.
Polyamine levels and ODC activity are elevated in a wide range of tumours, and high levels correlate with poor prognosis in breast cancer patients [ 25- 27].
Recently, survivin, a member of the IAP family, has been reported to be elevated in serum in RA, with high levels correlating with joint erosion in active RA [ 25].
In humans, plasma adiponectin levels correlated negatively with insulin resistance, and higher levels correlated with future weight gain in 1,063 women.
Organ expression analysis showed that these genes were expressed in all organs analyzed with the highest levels correlating with the richest accumulation of wogonin in the roots.
We demonstrated that crude NOx levels are significantly elevated in leptospirosis, with higher levels correlating with severity of the illness.
BRCA1 transcription is regulated with the cell cycle, and highest levels correlate with the G1/S-phase boundary [ 5, 9, 41, 47, 48, 49].
Ornithine decarboxylase (ODC1) is a key enzyme in the biosynthetic pathway of polyamines, and ODC1 at high levels correlates with poor outcome in neuroblastoma.
Co-expression of JAG1 and NOTCH1 at high levels correlates with poor clinical outcomes for breast cancer (110), and the majority of T cell acute lymphoblastic leukemia/lymphoma (T-ALL) cases are caused by gain-of-function mutations in NOTCH1(111).
The high expression level correlated with BKCa channel activity, invasion and TEM of the breast cancer cells metastatic to brain.
