Sentence examples for high km from inspiring English sources

Compared to the ubiquitously expressed GLUT1 glucose transporter, the GLUT5 fructose transporter has a high Km value for its substrate.

The mimic grafted on hydrophilic support exhibited high kcat and high Km values for N-acetyl tyrosyl para nitrophenyl ester.

Mitochondrial ME2 uses either NAD or NADP as a cofactor, has a high Km for malate and is allosterically activated by fumarate and inhibited by ATP.

The known XDH enzymes all exhibit a relatively high Km for NADP+ so that physiological boundary conditions are somewhat unfavorable for xylitol oxidation by NADP+.

This provides functional evidence of a profound reduction of high Km glucose transporter in beta cells.

Underexpression of beta cell high Km glucose transporters in noninsulin-dependent diabetes.

Unlike islet or liver cells, expression of glucokinase mRNA in anterior pituitary cells was not accompanied by expression of the high Km glucose transporter (GLUT-2) mRNA.

The high Km glucose transporter of islets of Langerhans is functionally similar to the low affinity transporter of liver and has an identical primary sequence.

The kinetic similarity of high Km glucose transport in liver and islets is readily understood in light of our structural analysis.

The liver has been shown to contain a facilitated diffusion glucose transporter with high Km for glucose that is structurally distinct from the low Km glucose transporters found in most other tissues.

Substrates for which we found high KM-values, were used with concentrations of up to 150 μM.