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Lithuania is a country of high incidence of TB despite a high coverage with bacille Calmette-Guerin (BCG) vaccination.
This method could be useful in countries like Lithuania where there is a high incidence of TB despite a high coverage with BCG vaccination.
Performance analysis studies have pointed out several flaws, e.g. poor coverage, high incidence of unclassifiable deaths, long delays and lack of systematic screening [ 16].
The T-cell-based method is more objective than the TST for identifying latent TB infection in children, especially in countries like Lithuania which have a high incidence of TB despite a high coverage with BCG vaccination.
Potential cross-reactivity is an important issue to be considered in the development of a new serologic test, particularly for countries with a high incidence of TB, high BCG vaccination coverage and high levels of exposure to environmental mycobacteria [ 35, 36].
This study reports the results of the first evaluation of ex vivo INF-γ-based aSPOT (TBSPOT TB) for the diagnosis of TB infection in children in a country of a high incidence of TB despite a high coverage with BCG vaccination, and presents the comparison of T SPOT TB results with those of the TST.
The results help to explain the high incidence of clinical disease despite good vaccination coverage.
Lithuania is a country with a high incidence of tuberculosis (TB), despite a high coverage with bacille Calmette-Guerin (BCG) vaccination.
The coverage for the PCV7 of 6.6% and 10.5% respectively for 2007 and 2008 during the LEAP study and the high incidence of CXR+Pn points to the need of high and sustainable coverage of pneumococcal vaccination.
On the other hand, the limited coverage of issues relating to rape and sexual violence in news stories does not reflect the high incidence of rape in South Africa.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com