Sentence examples for high grades of differentiation from inspiring English sources

Further analysis of TGF- β1, SPRY4, and P-p38MAPK proteins in relation to the degree of differentiation showed that both TGF- β1 and SPRY4 levels were significantly increased in RMS with low grades of differentiation compared with RMS with high grades of differentiation.

These tumors maintain a high grade of differentiation and low proliferation.

Ileal carcinoids maintain a high grade of differentiation and low proliferation.

That a higher grade of differentiation might not improve welfare has already been shown in econometric models [50].

Multivariate analysis demonstrated an independent lower risk of death for patients whose tumour expresses positive TTF1 staining (HR=0.51, 95% CI 0.30 0.85; P=0.01) and higher grade of differentiation (HR=0.40, 95% CI 0.24 0.68; P=0.001).

Multivariate analysis demonstrated a statistically significant and independent lower risk of death for patients whose tumour expresses a positive TTF1 staining (HR=0.40, 95% CI 0.25 0.65; P<0.0001), and a statistically significant and independent lower risk of death for patients whose tumour expresses higher grade of differentiation (HR=0.64, 95% CI 0.46 0.91; P=0.46 0.91

The present results indicate that high PROX1 expression is associated with the high grade of tumour differentiation and less favourable prognosis in the subgroup of patients with colon cancer.

Nestin could be detected in U251, 5-8F, 6-10B and CNE2 cells, which have a low grade of differentiation and a high grade of tumorigenicity, but not in the highly differentiated NPC cell line CNE1 or the NP69 cells, suggesting that Nestin expression may be modulated according to the state of malignancy of NPC cells (Supplementary Figure 7).

54 Patients with oral SCC and OSF are younger, show a higher grade of tumor differentiation, and a lower incidence of nodal and extracapsular spread.

It is reported that ERBB4 is frequently overexpressed in breast cancer, and the expression of transcripts encoding the cleavable ERBB4 isoforms was associated with ER expression and a high histological grade of differentiation [ 29].

Intermediate or strong staining for syndecan-1 was associated with a smaller primary tumour size (P = 0.0005) and higher histological grade of differentiation (P = 0.006) than negative or weakly positive staining.