Exact(7)
Specifically, children with very high generalized trust experienced greater loneliness and children with very low generalized trust had fewer friendships than children with midrange trust.
High generalized trust decreased the odds of restless sleep in women (OR = 0.75; 95% CI: 0.59 0.94); neighbourhood disadvantage increased the odds of restless sleep in women but not men (OR = 1.18; 95% CI: 1.01 1.38).
We hypothesized that a low Treg response to HIV infection might explain why most HIV controllers maintain high HIV-specific T cell responses but also high generalized T cell activation levels.
This unusually low Treg response in HIV controllers is therefore likely to be a significant contributor to the high generalized T cell activation and HIV-specific T cell responses observed.
We hypothesized that an unusually low Treg response to viral infection might allow some HIV controllers to maintain strong antiviral immune responses at the cost of at the cost of abnormally high generalized immune activation, potentially contributing to CD4+ T cell decline even in the absence of clinically detectable viremia.
In summary, we have observed that while most elite controllers maintain high HIV-specific T cell responses, most also have abnormally high generalized T cell activation levels, which may occasionally contribute to significant CD4 depletion even in the absence of clinically detectable viremia.
Similar(53)
Higher generalized anxiety symptoms were associated with a lower number of healthy behavioural changes.
We previously found that Rac3 KO mice show hyperactivity not associated with anxiety or curiosity, but to higher generalized basal activity (Corbetta et al. 2008).
The recent two-dimensional (2D) parametric formulation of the high fidelity generalized method of cells (HFGMC) reported by the authors is generalized for the micromechanical analysis of three-dimensional (3D) multiphase composites with periodic microstructure.
The high fidelity generalized method of cells (HFGMC) micromechanical method is extended to account for the fully (three-way) coupled TEM effects including Seebeck, Peltier, and Joule heat.
To this end, the high fidelity generalized method of cells (HFGMC), originally developed for micromechanical analysis of composites, is extended for the micro-electrical modeling in order to predict their spatial field distributions and effective electrical properties.
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