Sentence examples for high frequency of mutations from inspiring English sources

Mutational screening revealed a high frequency of mutations.

Samuels, Y. et al. High frequency of mutations of the PIK3CA gene in human cancers.

High frequency of mutations of the PIK3CA gene in human cancers.

We identified a high frequency of mutations in PTEN (50%) and genes involved in the endometrial cancer-related molecular pathway, which involves the IL-7 signaling pathway (PIK3R1, n = 1; AKT2, n = 1; FOXO1, n = 1).

DISCUSSION: We demonstrated a high frequency of mutations for exon 2 in specimens of primary testicular germ cell tumors, but not in benign tumors or normal controls.

This high frequency of mutations could, however, impede our antibody identification if mutations occurred in PCR primer-binding sites.

The corresponding residues in GyrA (83, 84 and 87) have a high frequency of mutation in quinolone-resistant bacteria.

TALE nucleases have recently been used for creating mutations in a rice gene involved in the development of bacterial blight disease, with a high frequency of mutation (20 30%), including bi-allelic mutations, at the T0 generation (Li et al. 2012).

A high frequency of mutation or deletion of PTEN occurs in some types of cancers.

(27) However, recent work suggests its high frequency of mutation may not imply a significant role in cancer.

This high frequency of mutation and the high copy number of mitochondria per cell suggest that mtDNA mutations may be useful markers for personalized assessment of cancer.