Sentence examples for high frequency of mutant from inspiring English sources

This study enables the development of a genetic test to efficiently reduce the high frequency of mutant UBE3B in Ayrshires, significantly improving animal health and reducing economic loss.

Furthermore, the absence of mutations in the OP target site and the high frequency of mutant carboxylesterase E3 indicate that metabolic resistance mechanisms have evolved predominantly in this species.

Several explanations were proposed for the detection of a high frequency of mutants on rifampin exposure, mainly related to methods or experimental variation (1 ).

The uniquely high frequency of mutants among invasive disease and carriage cc23 isolates suggest that these have an enhanced propensity to the mutant state for reasons as yet unknown.

The breeds with the highest incidence of RD had the highest frequency of mutant alleles while as expected the breed with the lowest frequency of mutant alleles also has the lowest incidence of disease (Table 2).

We detected a significant association of C3435T and G2677T polymorphism and UC with higher frequency of mutant allele and/or genotype carriers in the UC patient group.

This mutagenic preference made it possible to locate the interface between populations with and without the transposon simply by finding zones with a high frequency of singed mutant flies.

The high frequency of the mutant allele in Limousin most likely reflects the effects of selection for increased muscle mass.

The requirement of initially low and then gradually increasing R concentrations to select for mutant M296I [37], and the failure to select the same mutant by subjecting the same virus to 5 mM R, may relate to suppressive effects of the FMDV quasispecies when populated by higher frequencies of mutant genomes generated under elevated mutagenic intensities [71], [73].

Previous studies showed a high frequency of Pfmdr-1 mutant parasites (>60% of isolates), but did not explore their association with P. falciparum chloroquine resistance.

We targeted a region in between the two zinc fingers in the DNA binding domain of TRα, and the disruption was sufficiently efficient to produce a high frequency of tadpoles with mutant phenotypes in the injected F0 individuals.