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The high frequencies of recurrence and distant metastasis of adenoid cystic carcinoma (AdCC) emphasize the need to better understand the biological factors associated with these outcomes.
The poor prognosis of patients with HCC is largely because of the high frequencies of recurrence and metastasis after surgical resection, in addition to resistance to systemic chemotherapy (El-Serag, 2011).
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However, since frovatriptan seems to be superior to almotriptan in providing sustained relief from pain, this may suggest the use of the former in those patients with long-duration or high frequency of recurrence of migraine attacks.
One of the major obstacles for improved outcome after resection is the high frequency of recurrence.
The high frequency of recurrence is a current clinical problem in NMIBC.
Rapid malignant progression, dismal survival rate and high frequency of recurrence and metastasis remain the crux of HCC treatment.
Epithelial ovarian carcinoma is characterized by high frequency of recurrence (70% of patients) and carboplatin resistance acquisition.
The high frequency of recurrence, however, supports the hypothesis that a substantial number of patients have intrinsically drug resistant tumours [ 23].
EMPD of the axilla can be treated in various ways, which are rarely conclusive, either singly or in combination, because of the high frequency of recurrence [ 6].
14 TNBC represent approximately 15% of all breast cancers, 14 TNBC shows rapid growth and a high frequency of recurrence and metastasis.
The importance of new drugs for the treatment of dermatophytosis is highlighted by the fact that this disease affects approximately 40% of the world population, that only a small number of drugs are currently available for treatment, that azoles and allylamines have adverse gastrointestinal effects and that there is a high frequency of recurrence [ 18, 19].
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