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In summary, high fluoride and high fat increased serum TC and LDL-C levels individually and synergistically, and this would cause and aggravate hypercholesterolemia in rabbits.
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An increase in members of this family was associated with a diet high in fat, increased body weight and decreased fecal short-chain fatty acid concentrations in mice [ 25].
In another study [ 43], high fat feeding increased systolic blood pressure by ~40%, which would increase wall stress, but afterload and hydraulic resistance were constant in our isolated working heart preparation, so the effects of blood pressure were not relevant.
The high fat diet increased body mass, irrespective of vector treatment.
From this study it can be concluded that high fat diet increased arsenic induced oxidative stress.
High fluoride and high fat both increased serum levels of TC, HDL-C and LDL-C significantly (P < 0.05), and there was also a synergistic effect between high fluoride and high fat (P < 0.05).
A high fat diet increased body and epididymal fat pad weights, signifying greater body adiposity.
The high fat breakfast increased AUC by 4.25-fold and Cmax by 3.03-fold.
In this study, high fat diet increased weight gain and induced oxidative stress, which were attenuated by EBN feeding (Table 1 & Fig. 1).
Alk7ASKA and wild type mice gained weight at the same rate on a high fat diet, increasing by approximately 4 g by the end of the second week.
Both fasting and a high fat-diet increased the number of HDAC8-positive cells in the PVH (Figure 4C, D, G) but not in the VMHdm and LHA.
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