Sentence examples for high dose levels of from inspiring English sources

When M867 was given prior to radiation, apoptotic cells were decreased to half at both low and high dose levels of radiation.

Chronic exposure of rodents to high dose levels of drugs, food additives and environmental chemicals frequently results in liver enlargement.

Therefore, high dose levels of pemetrexed with FA/VB12 is expected to be tolerable enough for patients.

Currently, there is not any empirical data to consistently show linear improvements with dose [ 25, 26] and the adverse effects of high dose levels of MPD [ 27- 29].

Exposure of the lung to high dose levels of radionuclides produces a spectrum of progressively more severe functional and morphological changes, ranging from radiation pneumonitis and fibrosis to lung tumors.

As this was a proof of concept study a high dose level of CAT-354 was chosen to ensure target saturation at the supposed site of action, the lung.

Compared with the untreated group, a high dose level of CUR, ZO, AL, PC, and PPF produced a significant (p < 0.001) interference with muscle relaxation similar to that produced by 4 mg/kg body weight diazepam.

The relatively high dose level of 400 μg/kg was chosen to ensure a sustained and significant increase in blotted uterine weight during the 72-hr sampling period (Supplemental Data, Figure 1).

Despite the 2-week duration of dosing and the high dose level of capecitabine (2,750 mg/m), few patients (3 patients, 33.3%) experienced clinically significant hand-foot syndrome (grade 2 or higher), no patients experienced febrile neutropenia or required platelet transfusion, and no patients reported episodes of severe nausea/vomiting or stomatitis (Table 4).

In summary, compared to the submerged conditions, ALI exposure showed slight, but statistically significant enhancements in mRNA expression of IL-8, GM-CSF, and IL-6 for all dose levels and time points as well as for the high dose level of GCS (both time points).

Oral administration of a high dose level of PPF produced a significant (p < 0.001) prolongation of the latency time to the heat stimulus (with potency of about 50% of 5 mg/kg body weight morphine) compared with the untreated control, starting 30 min until 60 min after administration.