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To better understand the distribution of parameters that can give rise to high degrees of compensation and inducibility, we analyzed the system parameters for all networks that are both dosage compensated and inducible.
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However, there is a high degree of compensation following the ablation of PPARγ2.
Although consistent with the patterns observed for deletions in this study and by Stenberg et al. (2009), this explanation is inconsistent with higher degree of compensation of ubiquitously expressed genes: if these genes were universally copy number limited, one would expect the transcription level to be directly proportional to the number of copies of the gene.
We found that only networks with the topologies in Figure 1B and C are capable of showing simultaneously high degrees of dosage-compensation and inducibility.
High degree of transcriptional compensation in heterozygotes for a deletion suggests that recessivity of most loss-of-function mutations in Drosophila can be explained by transcriptional compensation.
The Danish labour market is characterised as a flexicurity system with a high degree of economic compensation in case of unemployment or reduced work ability (security) but also with a high turnover rate (flexible).
Each Bertelsmann division operates with a high degree of autonomy, and the compensation of its executives is based only on the performance of the division.
Despite scarcity, the relatively large share of water consumption in Italy does not cause any damages to human health due to the high degree of development which enables compensation strategies and avoids water scarcity related health effects.
It is likely therefore that the most essential genes should show a higher degree of dosage compensation in female birds.
In fact, the high degree of protection afforded by circumcision means that only extreme levels of risk compensation would lead to circumcised men being at more risk of infection than otherwise (Figure 6).
While on one hand many specific government control measures found a high degree of acceptance, a majority of study participants also thought that government control and compensation measures as a whole were insufficient.
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CEO of Professional Science Editing for Scientists @ prosciediting.com