Because of the high cost of instruments, expensive maintenance, lack of expertise, and less-than-ideal operational conditions, utilization of these techniques are not practical in low-income countries.
The high cost of scientific instruments, facilities, and payrolls made Big Science affordable only to government agencies or international consortia, drawing influence away from the universities, societies, and philanthropies that had been the main supporters of scientific research before World War II.
Because of the high cost of measurement instruments and the complex landscape, soil respiration has not been extensively investigated in Taiwan (Chang et al. 2008; Kao and Chang 2009; Hsieh et al. 2016).
The high cost of the instruments and short read lengths unfortunately limited adoption of this platform, and at the moment Helicos no longer sells instruments; instead it conducts sequencing via a service centre model.
Due to the high cost of the instrument, computerized sperm image analysis systems are used primarily for research applications.
Moreover, because of the high cost and extensive instrument time required, typically only a relatively small number of biological replicates are analysed in global proteome experiments.
The authors included most of the studies that were excluded from our review because of the high cost of the instrument or because they measured proprioception.
Furthermore, because of its overall complexity, the need for frequent calibration, and high cost as an instrument, multicolor FCM is often located in a central facility and operated by a skilled technician.
It was only achieved in very carefully controlled experiment environments where high cost and high precision lab instruments were employed [31 33].
However, due to the high cost of commercial TMA builder instrument, such method is not affordable for many pathology laboratories.
But a lack of repertoire as well as the high cost of replicating the original instrument impedes the uptake — and eventual mastery — of new electro-acoustic devices like Slabs.
