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Table gives motif examples with a high conservation rate in rice-sorghum orthologs.
In contrast, network-level conservation finds motifs by their global, i.e. genome-wide high conservation rate within syntenic promoters.
It reveals that clinical isolates originating from various geographic and biological sources exhibit a high conservation rate, suggesting that T. whipplei rarely interacts with exogenous DNA.
It reveals that clinical isolates originating from various geographic and biological sources exhibit a high conservation rate, indicating that T. whipplei rarely interacts with exogenous DNA.
This high conservation rate confirms the functional importance of non-coding sequences in Theileria, which goes beyond a role as passive intergenic spacers.
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The low values correspond to high conservation rates.
Signal conopeptide regions showed high conservation rates (from 61.4% to 100% identity).
Although we observed conserved instances of motifs at many different distances, the bin with the highest conservation rate was from 300 400 bp.
On this note, it was recently reported that the proximal poly(A) sites having higher variation of usage in different human tissues tend be to flanked by sequences with higher conservation rate [27].
A single gene (HS 3 Cj1135) had a higher conservation rate among enteritis-control strains.
How does the extent of conservation translate into function or survivability, since a higher conservation rate would suggest less tolerance for mutations?
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