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A high clinical score was directly correlated to iso-intense signal in DPFSE fat sat and to the percentage of regenerated hyaline cartilage, and inversely correlated to the percentage of newly formed fibrocartilage.
It is possible to have relatively mild arthritis (and minimal swelling) with a high clinical score.
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All patients showed high clinical scores after the operation and did not exhibit inflammatory reactions.
Arrows indicate termination of experiments in the sepsis placebo group due to high clinical scoring Fig. 5 Rat Grimace Scale and clinical scoring over time.
Patients with a failed previous femoral osteotomy had high clinical scores also, whereas lower scores were found in patients presenting with grade III osteoarthritis following osteochondritis dissecans (cases 8 and 9).
However, two out of the three remaining animals from this group had to be prematurely euthanized at 5 and 22 h due to the high clinical scoring (>6 points) as requested by the animal ethics committee.
Based on the clinical scores (Fig. 4B), the naïve and LVSCE alone immunized mice began to get sick rapidly, and by 7 8 days post-challenge all of the mice were either dead or had to be euthanized due to high clinical scores and body weight loss.
EAE lesions were observed in cerebellar white matter, especially in EAE mice with high clinical scores [ 25].
Unexpectedly, we found that some of the IL-10-deficient mice with high clinical scores developed high levels of anti-CII antibodies.
However, AO type A fractures showed the highest clinical score compared with type C fractures.
The girls had an higher clinical score than the boys: 6 [4 8] vs. 5 [4 7] p<0.036; the infants with a history of family atopy had a lower clinical score (5 [4 7] vs. 7[5 9], p = 0.002) and required a shorter time of oxygen supplementation (2[0 4]d vs. 1[0 3]d, p = 0.009).
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com