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AtHaspin showed relatively high expression in flower buds and flowers with high cell division activity.
Epithelial tissues generally have high cell division rates and this can lead to a high risk of proliferation-induced somatic mutations.
The expression of replication factor C complex (RFC2, RFC3 and RFC4) is indicative of proliferative potential (high cell division rates) of BRCA1 tumours.
The active cambium library is not over-represented with genes, which suggests that the genes we have identified are not simply general markers of high cell division.
Enrichment of nucleotide metabolism and DNA replication related categories could also reflect the high cell division activity during the initiation of cambium in the IN3 region.
AtHaspin-GFP driven by the native promoter was expressed in root meristems, shoot meristems, floral meristems, and throughout the whole embryo at stages of high cell division.
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With the new technique, the researchers can, for instance, target cells that have cancer properties (higher cell division rate or abnormal morphology) while sparing their healthy neighbors.
Thus, in lower organisms minimizing protein size would enable a higher cell division rate and result in lower DNA maintenance costs.
Group 1 genes were genes whose expression was higher at flower bud, decreased when approaching anthesis, and increased at 3DPA, signifying, higher expression at the higher cell division stages.
The smaller cell sizes in the area of the future second and third whorl compared to the innermost part of the floral meristem could indicate higher cell division rates.
At the centre of the meristem, stem cells divide only rarely, and part of their progeny is displaced laterally towards the peripheral zone (PZ), which exhibits a much higher cell division rate (Reddy et al., 2004).
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