Compared to FT, the main disadvantages of LSM for a first-line test are the lower applicability rate, the higher number of variability factors including a possible operator effect and the lower sensitivity for earlier stages of fibrosis [ 10].
The present study assesses the applicability rate of FT-AT, using the definition of high-risk profiles of false positive/negative induced by each component.
Independent factors associated with the high risk of false positives/negatives were HIV center, subSaharan origin, and a tertiary care reference centre, although the applicability rate remained above 97%.
The conversion system has high applicability and universality.
The mean applicability rate of Fibrotest was 99.03%.
JRCA indicates medium to high applicability for most indicators.
The robustness of our 2DPCA-IFS approach is that it gives the best time recognition, and thanks to the use of genetic algorithm and 2DPCA technique, which keeps a high recognition rate proving its applicability for real time system.
Also the fact that almost all of the participating persons scored positively on the content and style of the program, the high attendance rate, and the low drop-out is indicative for the applicability for this specific target group.
We acknowledge that the general applicability of our study results might be limited because of the high participation rate that was achieved.
