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Data from 433 patients hospitalized with advanced HF enrolled in the Evaluation Study of Congestive Heart Failure and Pulmonary Artery Catheterization Effectiveness (ESCAPE) trial were evaluated.
METHODS AND RESULTS: We studied 99 810 patients from 255 sites admitted with HF enrolled in Get With The Guidelines-Heart Failure between January 1 , 2005 and December 31 , 2010
METHODS AND RESULTS: We assessed the risk of an initial hospitalization for HF in 11 040 stable MI patients (no major non-fatal cardiovascular events or deaths within 45 days of randomization) without a prior history of HF enrolled in the VALIANT trial.
Acute heart failure (HF) is common in the elderly, but the association of age with clinical outcomes and prognostic factors has not been examined thoroughly.We analyzed the clinical and laboratory characteristics and the outcomes of 1,347 patients with acute HF enrolled in the VERITAS trial.
In patients with chronic HF enrolled in the GISSI-HF trial, increased estimated plasma volume was associated with worse clinical outcomes, independent of body weight changes [ 10].
This analysis showed that the beneficial effect of ivabradine observed in the patients with chronic HF enrolled in the SHIFT study was similar in patients who were receiving MRAs at baseline and those who were not.
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Compared with other recent trials, RED-HF enrolled more elderly [mean age 70 (SD 11.4) years], female (41%), and black (9%) patients.
The majority were also enrolled in Europe and none in the USA; MRA use is generally lower in the USA compared with Europe (and RED-HF enrolled a high proportion of patients in the USA).
FAIR-HF enrolled 459 patients with NYHA functional class II or III heart failure, an LVEF ≤40% (for patients with NYHA class II) or ≤45% (for NYHA class III), iron deficiency (defined as a ferritin level <100 µg/L or between 100 and 299 µg/L, if the TSAT was <20%), and a haemoglobin level of 9.5 13.5 g/dL.
METHODS AND RESULTS:We compared patient and hospitalization characteristics, resource utilization, and associated outcomes, among modern era acute HF patients enrolled in the GWTG-HF (Get With the Guidelines-Heart Failure) registry between 2011 and 2016, by varying severity of their acute HF.
A total of 232 baseline plasma samples from HF patients, enrolled in the DEAL-HF study, were available and included in the analysis.
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