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Facial anomalies are a heterogeneous trait in ICF syndrome and mainly include hypertelorism, epicanthal folds, abnormally low-set ears, and macroglossia.
Our results demonstrated heterogeneous trait evolution.
Much like alcoholism, impulsivity itself is a heterogeneous trait comprising multiple components.
Permanent hearing impairment is an aetiologically heterogeneous trait attributable to genetic and environmental causes.
EM is a heterogeneous trait and it is possible that clinical classification of sub-types would increase our power to detect genetic factors associated with the condition.
We have demonstrated that focal and non-focal epilepsy have distinct genetic architectures, reinforcing the view that epilepsy is a genetically heterogeneous trait and that association analyses should take account of clinically defined subtypes; but at the same time, we also found significant overlap between the two subtypes, meaning there is room for subtype definitions to be improved.
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The analysis of the design of a fresh start policy for a population endowed with unobservable heterogeneous traits is a complex task.
This approach is broadly applicable to more heterogeneous traits such as neuropsychiatric disorders, with 50% of previously identified genes within candidate intervals ranking either highest or second highest correlated gene using an autism-related expression module.
1– 3 Although MetS is considered to represent heterogeneous traits, insulin resistance and glucose intolerance associated with obesity are considered to be central to the pathophysiology.
Given that genetic variation or heterogeneous traits that might exist in the cell lines and limited resources and environmental challenges within the confined culture condition, fitness tests are spontaneously imposed and subclones with best adaptability will emerge.
According to the Hereditary Hearing Loss (HHL) homepage (http://hereditaryhearingloss.org/), over 140 loci for nonsyndromic HHL have been mapped, together with approximately 80 genes, and more than 1000 mutations have been identified in humans, making it one of the most genetically heterogeneous traits.
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