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The heterogeneous sensitivity of the HMCLs to RITA was not related to the molecular heterogeneity of the 14q32 translocation (p = 0.2, Anova test).
The heterogeneous sensitivity of the HMCLs to nutlin3a was not related to the molecular heterogeneity (p = 0.32, Anova test).To assess the toxicity of each drug against normal cells, peripheral blood mononuclear cells (PBMCs) from 3 independent donors were incubated for 3 days with serial concentrations of each drug.
This is why it is commonly applied in the heterogeneous sensitivity studies [14,15,19].
For heterogeneous sensitivity analysis, experimenters tend to form a mainstream processing style, which is discussed in the first part of this section.
Although most wireless technologies (such as ZigBee, Bluetooth, and WiFi) have been designed to work in the presence of interference, it has been observed that performance may degrade significantly because of heterogeneous sensitivity to detect or react to the presence of other nodes and technologies.
In addition, we observed the heterogeneous sensitivity toward aging within the six touch receptor neurons.
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Our results show that locally recurrent tumours exhibit heterogeneous sensitivities and are different from 'primary' tumour cells in sensitivities to immune cell killing, but they are not necessarily more or less sensitive.
Specificity of Ber-Ep4 and CEA was more heterogeneous than sensitivity and sensitivity was, in general, high.
A plausible biological explanation for such resistance is heterogeneous drug sensitivity of cells within the tumor mass.
Results were heterogeneous with sensitivity ranging from 0.06 to 1.00 and specificity from 0.28 to 0.94 (table 2).
First, the genomics data are heterogeneous in their sensitivity and specificity for relationships between genes.
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