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The heterogeneous result might originate from lack of a universal diagnostic system and the variability of TMD.
If a heterogeneous result is found, summary effect estimates from a random effects models should be considered (Riley et al. 2011).
Incorporating studies using different outcome definitions would result in a heterogeneous result difficult to interpret.
The somewhat heterogeneous result (p = 0.42) in this group of trials was essentially due to the more inconsistent survival data obtained by the trials using 5-FU as a combination partner.
For 2 of the 6 reviews [ 9, 10] where a significant result changed to a non-significant when we used a random effects model, the authors were cautious about their heterogeneous result and didn't base their conclusion on the significant finding they had obtained with a fixed effect model, which we consider a correct approach.
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Therefore, the purpose of this review is to summarize and elucidate the source of heterogeneous results reported in different studies.
For color contrast, the effects were smaller and more heterogeneous, resulting in little or no overall change in sensitivity across the population.
The variable pregnancy rate at first AI, however, yielded heterogeneous results among studies.
Moreover, although open access primary biodiversity data are heterogeneous, resulting from the good will of contributors and not from a well-planned sampling protocol30, they reflect our knowledge and practices in the study of biodiversity.
However, the predictive value of early improvement varies between studies, and the use of different antidepressants may explain heterogeneous results.
Heterogeneous results were found among those states where these were applied, despite using the same standardized training model for application.
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