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Early CD34+ cells are a heterogeneous population consisting of hematopoietic, endothelial and mesenchymal progenitor cells [8].
SP thymocytes are comprised of a heterogeneous population consisting of cells at different levels of maturity [46].
Such a validation can, for instance, be done by artificially creating a heterogeneous population consisting of known disease entities and then applying the clustering method to data from this population to see whether the method can detect the heterogeneity and recover the true entities.
This does not exclude the possibility that our Bregs could in fact be a heterogeneous population consisting of memory and transitional B cells in different states of activation.
The samples studied represent a heterogeneous population consisting of patients with localized and metastatic gastric adenocarcinoma, with different histological subtypes and subjected to adjuvant chemoradiotherapy or surgery alone.
Odek-Ogunde et al [ 5] found rates of lifetime alcohol use as high as 84% among students at a private university in Nairobi, Kenya, while Othieno et al [ 16] in a more heterogeneous population consisting of outpatients attending several Nairobi primary health care facilities found a lifetime alcohol use prevalence rate of 62%.
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Similar to the evidence on prevalence, studies on the determinants of CAM use also concern heterogeneous populations, consisting of a combination of women with low-risk and high-risk pregnancies.
Histologically, ocular adnexal MALT lymphomas are characterized by a heterogeneous cell population, consisting of monocytoid, plasmacytoid, and centrocyte-like cells, with occasional blasts in the marginal zone surrounding lymphoid follicles.
Embryonic stem cells are a heterogeneous cell population, consisting of subpopulations with variant expression levels of pluripotency-associated markers and differentiation status [41].
TECs consisted of a morphologically heterogeneous cell population consisting of cobblestone and elongated spindle-shaped cells.
An additional limitation of the study is the heterogeneous patient population consisting of unequal numbers of HBV mono-infected and HIV/HBV co-infected patients.
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