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The mosaic is baffling in its complexity: the cultures have interpenetrated one another as a result of constant migratory movements and through intertribal relations, leading to the obliteration of formerly significant differences, and to new cultural systems made up of elements of heterogeneous origin.
That is also why nineteenth and early twentieth century theories about human settlement of the continent can be classified into three noticeably different categories: those stating an in situ American origin of the humanity, those postulating a unique and recent origin for all Americans, and those suggesting a very ancient, multiple, and heterogeneous origin.
Noncompaction of the ventricular myocardium (NVM) is the morphological hallmark of a rare familial or sporadic unclassified heart disease of heterogeneous origin.
Samples from unknown risk factor patients displayed a mixed profile, with hypermethylation of several of these promoters, probably reflecting their heterogeneous origin (Figure 3 and Table S3).
This heterogeneous origin of miRNAs suggests each group of miRNAs with the same origin may be generated and maintained in a different transcriptional pathway.
Their heterogeneous origin may limit the detection of disease-specific exosomes in peripheral blood samples.
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Although each of these markers has been studied individually, they have not been used together to determine the overall marker profile of individual tumors and the possible heterogeneous origins in tumors.
The polyphyletic pattern suggested the possibility of heterogeneous origins of this species complex.
Metabolic diseases, with its heterogeneous origins, are complex disorders that need regular follow-up as well.
The idea that virtually all human melanomas and hepatocellular carcinomas have a similar phenotypic defect with regard to argininosuccinate synthetase is inconsistent with the heterogeneous origins of tumours.
The finding that heterogeneous origins result in common downstream biological pathways and outcomes provides the opportunity to develop rational treatment strategies that target the unique upstream initiating event and the common downstream effectors [ 4].
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com