Spaulding, D. & Morse, D. Purification and characterization of sulfatases from Haliotis rufescens: evidence for changes in synthesis and heterogeneity during development.
Measuring multiple omics profiles from the same single cell opens up the opportunity to decode molecular regulation that underlies intercellular heterogeneity in development and disease.
This new method can reflect the impact of reservoir heterogeneity and development option change on reservoir performance.
Tight gas reservoirs are characterized by low porosity, low permeability, low abundance, strong heterogeneity, high development cost, and great economic risk.
Heterogeneity in development and deployment platform: In essence, the current PaaS platforms offer a lot of similar architectural concepts towards application developers, but typically via vendor-specific solutions using different programming languages and supporting technologies [7].
Twin modelling furthermore provided evidence for considerable genetic heterogeneity during development with a genetic correlation of just 0.32 between ages 4 and 11 (Fig. 2, Supplementary Table S3).
Monitoring the heterogeneity and development of intracellular oxygen levels with high spatio-temporal resolution requires a molecular O2 biosensor that exhibits some important properties.
During the discovery stage, three genome-wide screens were carried out within children from the general population (ALSPAC), thus allowing for genetic heterogeneity during development through a cross-sectional design.
However, given the observed genetic heterogeneity during development, which is likely to extend into adolescence, and the increase in GCTA-heritability with progressing age, the lack of genome-wide findings needs to be placed in perspective.
Finally, changes in the composition and quality of peer groups and social interactions with age may draw out different genetic propensities (known as gene environment correlation), which could explain the genetic heterogeneity across development.
