Sentence examples for heritable sequence from inspiring English sources

Regulatory changes can occur through heritable sequence mutations or epimutations caused by altered patterns of DNA methylation, and there are examples of such mutations in both the coding regions of genes and associated transcription factor-binding regulatory elements that have had an historical impact on plant phenotype.

These acquired and heritable DNA spacer sequences are utilized by the Cas-encoded proteins in a defense system against mobile genetic elements, although intriguingly the CRISPR/cas elements are themselves associated with plasmids and phage (Touchon and Rocha 2010).

CRISPR/Cas is thus an adaptive and heritable immune system where sequence specificity is encoded in the spacer sequences.

This is often described as 'somatic evolution' because it requires a sequence of heritable genetic changes.

Conceptual models of carcinogenesis typically consist of an evolutionary sequence of heritable changes in genes controlling proliferation, apoptosis, and senescence.

This genomic insertion is crucial as it creates stable labelling of transfected cells with a random, unique and heritable combination of fluorophore sequences.

As will be discussed below, most mechanisms linked to epigenetic processes impact chromatin structure, which indicates that chromatin structure, like DNA sequences, contains heritable information that guides gene activity.

This, and the normal exclusion of viruses from the plant germ cells, reduce the likelihood of genome integration and suggest that a heritable maintenance of pararetroviral sequences has potential benefits for the host plants [ 10].

Being interested in the way that an initial premutational event is converted into a stable heritable mutation, we have sequenced stable mutations in a gene that has formed covalent adducts in vitro with N-acetoxy N-2-acetylaminofluorene (N-AcO-AAF, a model for the ultimate metabolite of the rat liver carcinogen 2-acetylaminofluorene, AAF).

Predictability from genetic sequence data requires heritable fitness variation among the sampled sequences.

Molecular genetic maps provide a means to link heritable traits with underlying genome sequence variation.