Sentence examples for heritable predisposition from inspiring English sources

This unique program is one of few in the nation that provides specialty oncology care and genetic counseling to children with heritable predisposition to cancer.

A small proportion of breast cancers are due to a heritable predisposition.

Epidemiologic data from families of serrated polyposis patients strongly suggest a heritable predisposition exists toward serrated colorectal carcinogenesis.

Whether IC unresponsive to physical exercise and smoking cessation identifies those with a heritable predisposition to more severe vascular events deserves to be addressed.

We show that loss or reduced expression of death-associated protein kinase 1 (DAPK1) underlies cases of heritable predisposition to CLL and the majority of sporadic CLL.

Similarly, in families with a heritable predisposition to breast cancer, time of birth, physical activity and obesity can profoundly influence risk.

Notably, these tumors also represent the sole manifestation of a heritable cancer predisposition syndrome caused by constitutional alterations of SMARCB1/INI1 tumor suppressor gene [ 5, 6].

Mutations in two major high penetrance genes BRCA1 and BRCA2 are well known, but they seem to be responsible for less than 20% of heritable disease predisposition [ 3, 4].

More starkly, core, heritable behavioral predispositions are always along for this grand, thrilling and dangerous evolutionary ride.

Detection of a MUTATION; GENOTYPE; KARYOTYPE; or specific ALLELES associated with genetic traits, heritable diseases, or predisposition to a disease, or that may lead to the disease in descendants.

Mechanistically, gene expression noise may contribute to reaching a disease threshold through the gradual accumulation of defects, by providing small random perturbations that amplify the effects of heritable and nonheritable predisposition or both.