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Moreover, the fact that these heritable markers do not parse T. cruzi strains along the same lines as traditional typing methods is strongly suggestive of genetic exchange playing a major role in T. cruzi population structure and biology.
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This co-activation could constitute a heritable marker for further genetic studies of JME.
A more recent focus in genetic research of PD has been to discover heritable trait markers of disorder vulnerability.
C-reactive protein (CRP) concentration is a heritable systemic marker of inflammation that is associated with cardiovascular disease risk.
DNA methylation is a heritable epigenetic marker that regulates gene expression without altering DNA sequence (Egger et al. 2004).
We therefore transformed the olive fly with construct OX3097, an fsRIDL system that had previously provided suitable fsRIDL strains for Medfly, incorporating genetic sexing, genetic sterilisation, and a heritable fluorescent marker [ 15].
Polymorphic SSRs were used to genotype the first DNA panel of 66 individuals, and then those having stable, heritable, and reproducible markers were genotyped on the second panel of other 66 individuals.
We found moderate level of epigenetic diversity, variation in CCGG methylation pattern and proved that many epigenetic markers are heritable and most epialleles follow Mendelian segregation pattern.
For the past 20 years, biomedical research community has spend huge efforts in identifying genetic markers for heritable diseases, through classical linkage studies [ 231] or recent Genome-wide association studies [ 232].
For each method, the article also examines major findings in alcoholism and possible translational applications of these electrophysiological measures to diagnosis, prevention, treatment, and rehabilitation, including the utility of these measures as highly heritable and sensitive endophenotypic markers for gene identification, with potential for possible drug development for alcoholism.
Nonword repetition is a good marker for heritable SLI (46).
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