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Bipolar disorder is a highly heritable illness that onsets in adolescence and young adulthood.
Existing psychological screening tools do not take into consideration of 'risk factors' associated with heritable illness or genetic-related stressors.
A more informed way to rank brain measures for genetic screening is to use the endophenotype ranking value (ERV; Glahn et al. 2012), which aims to rank biomarkers in terms of their promise as endophenotypes for any heritable illness.
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The latest data suggest that even the most common heritable illnesses, such as diabetes and heart disease, are linked to many different variants, each of them relatively rare.
Bipolar disorder (BD) is a heritable psychiatric illness characterised by cyclic mood episodes of opposite polarity alternating with intervals of well-being (Goodwin and Jamison 2007).
The presentation of a highly heritable psychiatric illness such as bipolar disorder does not differ in cases drawn from genetically unique Anabaptist populations.
These results also show that the presentation of a highly heritable psychiatric illness such as bipolar disorder does not differ much in the genetically isolated Anabaptist population, implying that genetic insights enabled by isolated populations might also inform our understanding of psychiatric disorders in the general population.
Nor does he mention, even in passing, the question of heritable mental illness, or the fact that Hemingway's father took his own life, as later did his sister, his brother and his granddaughter.
Bipolar disorder (BD) is a heritable chronic psychiatric illness standing among the leading causes of disability worldwide (Collins et al. 2011; Gore et al. 2011; Whiteford et al. 2013).
Tens of thousands of children die each year in high income countries from trauma, prematurity, heritable disorders, and acquired illnesses.
Psychosocial risk factors for psychiatric illness are moderately heritable.
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