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However, being genetic markers, they are applicable only on heritable conditions, which is often a neglected fact.
As expected, congenital and heritable conditions were more common in children, while age related diseases were predominant in the elderly patients.
Heritable conditions also contribute to the occurrence of these tumours that include Li-Fraumeni syndrome, retinoblastoma and Werner's syndrome among others [ 3].
When services are developed for heritable conditions in other specialties, this 'familial' emphasis can demand a shift in thinking for health professionals.
With rapid improvements in technologies, we are seeing the leading edge of the applications of whole genome sequencing (WGS) in practice primarily in the identification of rare heritable conditions [ 31].
The association between chromosomal radiosensitivity and increased susceptibility to cancer has been demonstrated for a number of cancer-prone heritable conditions, most notably ataxia telangiectasia (Parshad and Sanford, 2001).
Similar(51)
But new studies have indicated that although prosopagnosia can result from a stroke or traumatic brain injury, it is a heritable condition that is sometimes present from birth.
Luria also notes that Shereshevsky had an extraordinarily strong case of synesthesia, the heritable condition in which the senses become intermingled in the mind, and the psychologist recognized that this had something to do with Shereshevsky's powers of recall.
In addition, TD is a highly heritable condition, and investigations currently underway may identify the genetic variants that underlie this condition.
Fibrodysplasia Ossificans Progressiva (FOP) is a rare, heritable condition typified by progression of extensive ossification within skeletal muscle, ligament and tendon together with defects in skeletal development.
Essential hypertension is a common multifactorial heritable condition in which increased sympathetic outflow from the central nervous system is involved in the elevation in blood pressure (BP), as well as the exaggerated morning surge in BP that is a risk factor for myocardial infarction and stroke in hypertensive patients.
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