Sentence examples for heritable abnormality from inspiring English sources

In these cases, death is presumed to be secondary to a lethal and potentially heritable abnormality of cardiac ion channel function.

Congenital spine deformities occur with an approximate frequency of 0.5 1 per 1000 live births (Sparrow et al. 2011) and may arise sporadically or as the result of an underlying heritable abnormality in genes that contribute to vertebral development.

In these cases, death is presumed to be secondary to a lethal and potentially heritable abnormality of cardiac ion channel function caused either by an aberration in the genes encoding these proteins, or genes encoding "accessory" proteins essential to ion channel function.

Following this attractive targets, Goldstein's findings allowed for establishing the hypothesis that diabetics fibroblasts replicative life span did proportionally decline with diabetics' predisposition under normal glucose concentrations, concluding that a persistent, heritable abnormality is present in mesenchymal tissues of overt diabetics and genetically predisposed subjects [ 15].

In addition, there was no known heritable genetic abnormality documented, specifically none were noted to belong to a family with Familial Adenomatous Polyposis or Hereditary Non-polyposis colorectal cancer syndromes.

To review evidence regarding the effects of male age on germinal and heritable chromosomal abnormalities using available human and rodent studies and to evaluate possible underlying mechanisms.

Moreover, exaggerated medial prefrontal cortical and subcortical (putamen and amygdala) responses to emotional signals have been observed in bipolar I patients and their nonbipolar relatives, suggesting that such responses may represent heritable neurobiological abnormalities underlying bipolar disorder [ 49].

Objectives: heritable connective tissue abnormalities and arterial hypertension may predispose to aortic dissection.

These samples are distributed among several collections and represent a variety of chromosomal abnormalities, heritable diseases, numerous distinct human populations, and apparently healthy individuals.

All of these cell lines and DNA samples are categorized into several collections representing a variety of disease states, chromosomal abnormalities, heritable diseases, distinct human populations, and apparently healthy individuals.

To examine if the abnormal traits were heritable, we obtained the F2 generation from the May samples and estimated the abnormality rate of adults as 33.5% on average.