Sentence examples for hereditary setting from inspiring English sources
To our knowledge, our study is the first report where the effect of BRCA1 inactivation and reconstitution on drug sensitivity is evaluated in cells derived from a tumour arising in the BRCA1 hereditary setting.
We reasoned that BRCA−/− breast cancer cells offer the specific molecular pathology milieu for experimentally addressing the issues relevant to the management of breast tumours in the hereditary setting.
Taken together, these findings suggest that changes in the sensitivity to antitumor agents could indeed be a part of the phenotype of breast carcinomas arising in the hereditary setting and could be of relevance in the treatment of these tumours.
In this hereditary setting, the genotype-phenotype correlation is not always present: gene carriers and family members sharing the same PTCH1 germ line mutation have a variable phenotype [ 3].
Although further studies are needed to unravel the timing of occurrence of MLK3 mutations, as well as its associated cellular effects and signalling pathways, our data put forward a new candidate biomarker and/or an attractive potential target for future therapy in MSI gastrointestinal tumours, namely in the hereditary setting.
If W is a hereditary set, then e(W) is a central idempotent in ({widehat{L}}(Gamma ).) If a, b are distinct elements from ({ pp^*mid pin Arr(W }) then (ab=ba) by Remark 1.
A hereditary set is saturated if, for any regular vertex v, (r(s^{-1} v))s^{-1} v H) impliesubseteq).
Reducing ultraviolet radiation (UVR) exposure may decrease melanoma risk in the hereditary melanoma setting.
Many of the classical conditions of oligarchic rule were found until the 20th century in those parts of Asia in which governing elites were recruited exclusively from a ruling caste a hereditary social grouping set apart from the rest of society by religion, kinship, economic status, prestige, and even language.
I like that from him (especially since male pattern and hereditary baldness will set in eventually).
The analysis identified three disease phenotypes enriched within the data set: Hereditary fructose intolerance syndrome (P = 4.39 × 10−5), cerebral toxoplasmosis (P = 1.14 × 10−3), and agoraphobia (P = 1.17 × 10−4) (supplementary table S1, Supplementary Material online).
