Sentence examples for hereditary modification from inspiring English sources

Maternal IQ is typically included in regression modeling of developmental studies on the effects of neurotoxic contaminants such as lead or PCBs to account for hereditary modification (Winneke 2011).

Although Agassiz was quite familiar with the factual evidence concerning environmental change, variability, and hereditary modification on which Darwin built his arguments, he held that the organic world represented repeated interventions by a supreme being in line with Cuvier's doctrine of catastrophism.

How could Darwin possibly have anticipated some of the many aspects of major rapid hereditary modification that now loom so large in our thinking about evolutionary variation?

This supports the importance of the contribution of genetic background to risk modification in hereditary cancer syndromes (Byrnes et al, 2008).

The big unknowns were how heredity worked, how change occurred, and how hereditary variation (called "descent with modification") transformed itself into useful biological diversity.

As there is no equivalent of tumor material testing in hereditary breast cancer, alternatives for modification must be found within the current diagnostic process.

TSGs are frequently dysregulated by mutations or epigenetic modifications in both hereditary cancer syndromes and/or somatically non-hereditary cancers and are also responsible for the initiation and progression of all types of cancers, thereby composing an essential class of signalling molecules within the cell.

Tumor-associated stromal cells maintain their altered phenotype in cell culture during prolonged passage [ 13], indicating hereditary changes such as epigenetic modifications, as genetic alterations are very rarely detected [ 14].

The term mutation is often used to refer to a genome variation that is related to certain hereditary disease or cancer, while polymorphism indicates a modification that can be neither harmful nor beneficial (65).

Such future modification of the flexible configuration of the Hereditary Hearing Loss Arrayed Primer Extension microarray would improve its impact as a diagnostic tool.

We used a similar strategy to examine effect modification by family history category, comparing women with a hereditary family history of cancer with women without such a family history.