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The hereby generated data-sets represent a solid amount of knowledge on the dynamic transcriptional activities during the investigated fermentation stages.

The hereby generated and optimized in silico tools now enabled us to identify and further characterize the neolignan honokiol, a major bioactive constituent of the traditional Chinese herbal drug Magnolia bark, as novel non-adipogenic partial PPARγ activator.

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Sodium absorption hereby generates the osmotic gradient, drawing alveolar fluid through alveolar epithelial aquaporin channels and paracellular pathways [ 4, 5].

Through in vitro reprogramming of somatic cells via induction of the four transcription factors OCT4, SOX2, KLF4 and MYC ; pluripotency can be re-established hereby generating induced pluripotent stem cells (iPSC ., During reprogramming, genome-wide changes in the transcriptome and the chromatin structure are induced to achieve the switch to the pluripotent state.

By more detailed SEM imaging of the external antennal anatomy, we hereby aim to generate a sensilla map for C. hemipterus comparable to that of an existing map for C. lectularius produced by Steinbrecht and Müller [20].

40 The observed overactivity of preSMA might therefore constitute an aberrant striatal feedback signal that causes an abnormal induction of internally generated movements and hereby contributes to the emergence of dyskinesias.

A database consisting of 3500-fragments were used to enumerate de novo designed imidazolone and oxazolone derivatives and hereby more than 50000 novel small molecules were generated.

The process of analysis hereby developed from organising the data to organising ideas generated from the data, as described by Starrin (12).

Strong features of our software are the absence of a need for additional data entry since the software can extract all relevant information from the hospital information system, and the integration with the hospital charting system, which can put generated patients' letters back in the system after the letters being approved, hereby reducing the clinician's workload.

In this study, we generated mice transgenically over-expressing the mitochondrial protein frataxin, which promotes mitochondrial energy conversion by controlling iron-sulfur-cluster biogenesis and hereby mitochondrial electron flux.

Microarray is a well-established, cost-effective, high-throughput technology able to simultaneously measure the expression levels of thousands of genes and hereby offers an efficient way to generate a snapshot of the entire transcriptome.

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