The amplification of epidermal growth factor receptor (EGFR) in triple negative breast carcinomas (TNBC) suggests its potential therapeutic application, as for HER-2, using standardised methods of measurement.
Like thousands of other children in year 6, my eldest daughter has her key stage two standardised tests this week.
However, the study psychiatrist has been specifically trained and based her clinical judgment on a standardised guideline.
These instruments require the patient to report his or her health state with a standardised generic health state classification system, which is then converted into a health utility score using utility weights derived from the general population.
Ms Davis also held her own in an exchange over standardised testing, although she dodged several questions about how she proposed to pay for her own education proposals, such as free early education.
In breast cancer, HER-2/neu amplification or overexpression, according to standardised criteria, has been described as a marker predicting both response to treatment and poor prognosis with nodal metastases (Slamon et al, 1987; Menard et al, 2000; Yamauchi et al, 2001).
Even if every pupil in the state system turned up on time, never missed a day, learned to recite her times-tables to 12, aced every standardised test, and devoted herself to reading upright classics that would delight an anxious Victorian middle-class striver, they will not become educated.
Ki-67, p53 and ER immunohistochemistry, and Her-2/neu amplification analysis by CISH involves simple, standardised and established methods that can provide valuable prognostic information on T1N0M0 breast cancer.
Despite the differences seen in staining location, we demonstrate that in terms of relationships with pathological variables, HER family members and prognostic importance, when tested under standardised conditions on the same set of tumours both antibodies provide generally similar results.
Each was given a standardised reading test while his or her brain was scanned by DTI.
