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And yet the most significant involvement of women is restricted to the aesthetic, rather than to the physical domestic aspects of gendered relationships.
MLK4 knock-down resulted in decreased phosphorylation of NF-κB at 5 and 10 min after TNF-α stimulation, but there were no differences at 25 min, indicating that the most significant involvement of MLK4 in activation of NF-κB pathway takes place at early stages of pathway activity (Supplementary Fig. 9a and b).
But there are an even smaller number of survivors of the Pearl Harbor attack -- the earliest and most significant involvement by our military in World War II -- still alive.
This subject occupied her throughout her life and eventually provided her most significant result.
4. Her work with the Underground Railroad was her most significant contribution.
It represents a big departure from her most significant previous role, in 2006's "Dreamgirls".
The Australian beat Karolina Pliskova for her most significant victory, showing the promise of many more.
She's remembering her most significant influence now passed.
Some of her most significant aid came from women.
One of her most significant contributions did not bring her a nomination, however.
Indeed, her grandson has written, "My grandmother considered [Social Security] her most significant accomplishment.
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