Sentence examples for hepatic mixed function oxidase from inspiring English sources
The role of the hepatic mixed function oxidase system may be especially important in conferring teratogenic risk.
A positive correlation in the effect of endosulfan on hepatic mixed function oxidase activity and hepatic phosphatidylcholine is observed.
Cyclophosphamide (CP) administration to rats in a single i.p. dose (200 mg kg-1), while producing urinary bladder toxicity and 30-40% depression of the hepatic microsomal mixed function oxidase (MFO), failed to produce any depression of MFO activities in extrahepatic tissues such as lung, kidney and intestine.
The mixture of PBBs in FireMaster BP-6 has been demonstrated to constitute potent inducers of hepatic and extrahepatic mixed function oxidase (MFO) enzymes.
Hepatic microsomal mixed function oxidases from rats, mice, and humans were equally effective in transforming vinyl chloride into alkylating agents in vitro.
However, CP requires metabolic activation by hepatic microsomal cytochrome P450 mixed function oxidase system for both its therapeutic action and its toxicologic actions [ 1].
The six other domains are mainly enzymatically functional and include serine/threonine protein kinase catalytic (STKc), mixed function oxidase (P450), protease (Trypsin-like protease, peptidase M13), esterase (carboxyesterase), and Ubiquitin-conjugating enzyme E2 catalytic domains.
CYP are the mixed function oxidase enzyme family (EC 1.14.14.1: mono-oxygenases that contain iron-dependent protohaematin IX).
Mixed function oxidase activity of cytochrome P450s was measured following de Sousa et al [31].
We found significant daily rhythms in ECOD activity, reflecting mixed function oxidase activity, which has been associated with insecticide resistance and overexpression of cytochrome P450s in Drosophila [31].
The cytochrome P450 (CYP450) is a superfamily of hemoproteins that are the terminal oxidases of the mixed function oxidase system involved in the biotransformation of endogenous compounds and xenobiotics.[1] To date, 57 genes and 58 pseudogenes of the CYP450 superfamily have been characterized from the human genome.
