Furthermore, AuNP did not induce significant damage in the liver since the activity of neither hepatic indicator (aspartate aminotransferase and alkaline phosphatase) increased.
In all groups of mice, the hepatic index (HI), an indicator of animal health, was measured.
Two months after completing the treatment, blood and liver tissues were collected to examine liver function and hepatic fibrosis indicators.
Although we did not fractionate the LDH, we did not see clinically significant correlations between elevated LDH and elevated hepatic transaminases or indicators of anemia such as lower hemoglobin and hematocrit (data not shown).
Our study confirmed the discriminatory power of albumin and ALP in predicting overall and disease-free survival by showing highest c-indices among other indicators of hepatic dysfunction including bilirubin, ALT, Child-Pugh score, and MELD score.
Mean velocity (Vmean), average portal blood flow volume (PBFV) and congestion index (CI) are important indicators in hepatic evaluation, mainly to detect alterations such as chronic hepatic diseases that lead to portal hypertension [ 1].
Consequently, we achieved a high significant correlation between the study parameters and found it a reliable indicator of hepatic cellular injury in the hepatitis C patients.
GGT is used as a sensitive indicator of hepatic inflammation, fatty liver disease, and hepatitis; most recently, it has been implicated in oxidative stress associated with glutathione metabolism (38).
No clinical symptoms of ricin intoxication were observed and the serum concentrations of the enzymes alanine aminotransferase (ALT) and aspartate aminotransferase (AST), which are indicators of hepatic function, were not changed across diets (P > 0.05).
Albumin secretion and glucose consumption were chosen as indicators of hepatic cellular phenotype, as previously reported [38] [40].
