Sentence examples for hence profound from inspiring English sources

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Hence, profound resistance to DCA correlates with acquired resistance to multiple other drugs each of which is known to cause cell death through very different mechanisms.

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These phenomena hence have profound consequences for the multi-billion dollar aerospace and space technology sector (e.g. Feynman and Gabriel 2000; Pirjola et al. 2005).

Mutations in the fibrillin-1 gene FBN-1 may cause aberrant fibrillin microfibril assembly and hence the profound aortic pathologies which characterize Marfan syndrome [50].

Moreover, changes in endothelial membrane potential in situ via myo-endothelial gap junctions influence the membrane potential of underlying smooth muscle cells (Beny and Pacicca, 1994) and, hence, have profound influence on vascular tone.

Hence, a profound limitation of the analysis is that it does not consider the broader contribution of the individual to the country's economic growth and the future increased demand for goods and services.

Its absence from mouse hair cells results in the loss of the mechano-electrical transduction process, hence in profound deafness; we also provide genetic evidence that this conclusion also applies to humans.

Hence, the profound effect of double depletion of Rabs 5 and 11 on virus production likely reflects the involvement of these two Rabs in the sequential trafficking of virus glycoproteins through this network and suggests that the virus exploits the normal trafficking of PM in its envelopment strategy.

Scientific management, moreover, demanded strict supervisory control over the workplace and hence posed a profound threat to customary patterns of workers' autonomy in the labour process.

In particular, the Jagged1-Notch pathway seems to be a good candidate to participate in the susceptibility and therapy of MS. Hence, a more profound study of its regulation may help to understand its implication in MS and its potential for therapy.

Hence, the more profound increase in atopy with age in the urban site could be attributed to the higher mean age of the urban participants in this study.

Hence, despite the profound and common changes in gene expression that all DC subsets undergo during MCMV infection in vivo, each activated subset keeps track of its specific lineage through maintained selective expression of a transcriptomic fingerprint, as further illustrated with individual gene expression profiles (Supporting Information Fig. 1A).

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