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Since ticagrelor does not prevent ADP binding, it is hypothesized that it acts by inhibiting the receptor conformational change and G-protein activation induced by ADP binding, hence "locking" the receptor in an inactive state and inhibiting ADP signaling [ 36].
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In this model, the acetylation of Smc3 allows conformational changes to occur that cause a tightening of the cohesin kleisin interaction and hence locks the complex onto chromatin.
In the nonstressed state, a H3S10ph-associated factor (referred as "X factor") prevents HDAC1/2/3 from accessing H4K5ac/K8ac for deacetylation and hence locks up the majority of Brd4 onto chromatin).
But the trend in recent deals is for enhanced lock-ups, hence, lock-up creep.
It can be clearly seen that the original shear strain and assumedshear strain are not compatible and hence the shear locking exists for very thinshell cases.
In addition, a novel domain-based selective scheme is proposed leading to a combined ES/NS-FEM model that is immune from volumetric locking and hence works very well for nearly incompressible materials.
Three, Obama set the bureaucratic and military gears in motion back in March at the time of Super Afghan Review I. Hence, he is locked in through his own poor judgments on all three fronts: intellectual, political and military.
Hence, independent coding with strong phase locking does not quantitatively explain the changes in sequence properties with running speed.
It becomes a case of a would-be jailer locking himself into a prison and hence becoming a prisoner himself.
Hence, the higher the flow rate was, the stronger the spike phase locking to gamma phase was.
Hence, alexithymics may get locked into a negative cycle of repeat negative behaviour.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com