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It is reported that dihydrotanshinone present in the root of the plant can inhibit the uptake of calcium ions in vascular smooth muscle cells and hence exert vasorelaxant effect [52].
In addition, we show that this HRG-fragment can bind to endothelium in the presence of activated platelets and hence exert its antiangiogenic effect [3].
These negative consequences may very well be the cost paid to maintain the honesty of the social signal [3], and hence exert a direct influence on the development of the ornament.
Indeed, disorder provides a solution to reduce both genome size and molecular crowding, where a single gene would (i) encode a single (regulatory) protein product that can establish multiple interactions via its disordered regions and hence exert multiple concomitant biological effects, and/or (ii) would encode more than one product by means of overlapping reading frames.
SX can improve hemodynamic and myocardial oxygen metabolism, reduce the degree and scope of myocardial ischemia, and hence exert notable anti-anginal ischaemic effect.
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We have recently demonstrated that the complementation of oncolytic virotherapy with gemcitabine accentuates its immunostimulatory effects, hence exerting superior antineoplastic activity.
Quantitative and qualitative cell uptake studies demonstrated a significant uptake of IDB NLCs (3-fold increase) and nile red-labeled IDB NLCs (NR IDB NLCs) at 2 h, respectively, hence exerted improved photoprotective effects.
Tensile strength determination is particularly relevant when TEOS treated samples are under examination, as the formed silica gel can either create chemical bonds with the samples, hence exerting a proper binding action, or else just deposit inside stone pores, hence not giving significant benefit in terms of cohesion [1].
The combined interpretation of the binding and activity data suggests that XOS binds to the active site of TrCel7A and hence exerts competitive inhibition.
In particular, miR-200b and miR-15b (which are downregulated in CDDP-resistant TSCC cells) turned out to actively inhibit the EMT (hence exerting oncosuppressive effects) by targeting the polycomb ring finger oncogenic factor BMI1.
This pattern might be realized if at the start of every host-generation, the parasite population is small (and hence exerts only a negligible selection on the host-population) and later, after a number of parasite generations, reaches an appreciable size (and thus exerts appreciable selection on the host after it has adapted to the host population).
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com