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Hence, alterations in both hydrological and geotechnical conditions result, changing the triggering thresholds for further failure.
Hence, alterations in deiodinase balance can affect downstream tissue-specific TH signaling and local action.
Hence, alterations in the DDR pathways may accumulate these lesions to trigger hepatocarcinogenesis and also to facilitate advanced HCC progression.
We hypothesized that alterations in mRNA abundances (and hence alterations in functional profiles) are regulated, in part, by specific transcription factors.
Hence, alterations in physiological processes affect the mean phenotype both through plastic responses and by changing the species composition of phytoplankton communities.
Hence, alterations in the encoding gene are likely to lead to disorders in the various metabolic pathways associated with liver function.
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Hence, alteration of GS level by modifications of its transcription and/or degradation rate constitutes a novel form of regulation of the glycogen metabolism.
Hence, alteration of the histidine domain of Aβ prevented neuronal binding and drove Aβ to enhanced fibril formation and subsequent amyloid plaque deposition - a potential mechanism for removing toxic species of Aβ.
Hence, alteration of surface membrane microdomain lipid and protein composition via inhibition of syntaxin-6 function was found to decrease the internalization of cargo molecules by caveolae [ 61].
TACC3, in complex with the Ch-Tog protein, is essential in spindle microtubule growth and stability [ 14, 49]; hence, alteration of TACC3 localization following MK-0457 treatment could explain, at least in part, the aberrant spindle formation in TT cells.
Hence, alteration (e.g., activation and inactivating mutations) of genes (e.g., PTEN, KRAS, and LKB1) whose products regulate the mTOR axis will result in hyperactivation of the axis in certain types of cancers.
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