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Hence, aged or young CD45.2+, Thy1.2+ C57BL/6 mice were adoptively transferred with young naïve (CD44lo, CD62Lhi) CD45.1+ TCR transgenic T cells that are reactive to the SINFEKL OVA257 264 peptide presented by MHC class I (cells denoted as OTI) and young naïve Thy1.1+ transgenic T cells that are reactive to OVA323 339 peptide presented by MHC class II (cells denoted as OTII).
Aging is the greatest risk factor for AD; hence, aged rodent models that show cognitive impairment may provide a useful choice for testing investigational therapies targeting mechanisms of neuroprotection, learning, and memory.
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Hence, ageing.
Hence, aging may impact alloimunity via multiple effects, although it is unclear whether altered cellular alloimmunity with aging is due to impaired priming by dendritic cells (DCs) or due to defective intrinsic T cell function.
ROS have been viewed as mostly deleterious to health and hence aging.
Elevated expression of proteasome or disaggregase activities can prevent the accumulation of aggregates and hence aging of budding yeast [ 56].
However, IR's other dominant deleterious effects, and hence aging mechanisms, may be associated with apoptosis and inflammation.
Hence, age estimation based on the count of LAGs in rauisuchian osteoderms appears to be reliable only in the early stages of ontogeny.
By 18 December, the team had published its results on the Internet: a catalogue of 323 distant galaxy candidates, along with their redshifts--a measure of distance and, hence, age.
Because distance measurements are used to calculate the brightness--and hence age--of stars, the new data indicate that Orion's stars are older than previously thought, which makes them consistent with current theory about stellar evolution, Bower notes.
Hence, age is inherently controlled for in all analyses.
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