Sentence examples for hence activate from inspiring English sources

TNFα has in vitro been shown to phosphorylate and hence activate, the inactive forms of extracellular signal-regulated kinase (ERK), p38 proteins and Jun N-terminal kinases (JNK) [20].

Since the TN always spike first in the network, they tend to strengthen, hence activate, synapses onto all neurons.

It has been suggested that 940-nm and 980-nm diode lasers also are able to induce cavitations and hence activate irrigants [ 22].

Proprotein convertases are subtilisin-like serine endoproteases that cleave and hence activate a variety of proproteins, including growth factors, receptors, metalloproteases, and extracellular matrix proteins.

Xiao et al. revealed that increased ROS can induce the destruction and hyperphosphorylation of CDC25c, a phosphatases that can dephosphorylate CDK1 in Thr14 and Tyr15, and hence activate the CDK1/cyclinB1 kinase complex [ 20].

This is exemplified by its ability to promote the nuclear translocation of β-catenin in gliomas, and hence activate a programme of Wnt target genes (Zhang et al, 2011).

For example, miR-130b directly represses MST1 and SAV1 expression in human glioblastoma cells and hence activates TAZ and TEAD transcription activity (Zhu et al., 2015).

Caspase-1 was first described as the IL-1 converting enzyme responsible for processing and hence activating proIL-1β to its active form [1] [3].

After the peptidoglycan detection the NOD proteins recruit the downstream adaptor molecule RIP2 hence activating proinflammatory pathways such as NF- κB and mitogen-activated protein (MAP) kinases such as p38, ERK, and JNK [ 128].

AMPK, one of the major kinases sensing glucose, phosphorylates AMOTL1 and hence activates LATS1/2 (DeRan et al., 2014).

As known, TβRI, or activin receptor-like kinase, phosphorylates, hence activates, the transcriptional factors Smad2 and Smad3 enabling them to translocate into the nucleus [14].