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The scores of 0, 1, 2 and 3 were defined to illustrate the level of severeness of the manifestation as absence of pulmonary hemorrhage, hemorrhagic focus (minimal), hemorrhagic area (moderate) and hemorrhagic diffusion (marked), respectively.
In liver, thread-like leptospires were predominantly found closely associated with hepatocyte as well as granular deposits in Kupffer cells after 48 h p.i.. Lungs of infected guinea pigs showed significant microscopic hemorrhage with intact leptospires in every hemorrhagic area detected by immunohistochemistry, whereas rare leptospires could be detected in none hemorrhagic areas.
d Abdominal magnetic resonance imaging (MRI) shows a hyperintense component on T2-weighted imaging compatible with the hemorrhagic area Fig. 2 Findings of FDG-PET.
Pollutants cause alterations in the liver, lysis of hepatocytes resulting in necrosis, breakdown of blood vessel resulting in a hemorrhagic area, cirrhosis, and ultimately death.
Magnetic resonance imaging (MRI) of the abdomen showed hyperintense components on T2-weighted imaging, compatible with the hemorrhagic area (Fig. 1d).
At 48 h p.i., abundant leptospires were detected in the dermis and subcutaneous of hemorrhagic area and were rarely detected in adjacent none hemorrhagic areas (data not shown).
Similar(53)
The mass may present cystic and hemorrhagic areas [46].
Vascular changes included significantly increased tortuosity and diffuse perivascular sheathing Fig. 2 FFA of left eye revealed some capillary non-perfusion areas and blocked fluorescence in hemorrhagic areas.
Microscopic findings showed a proliferation of markedly atypical polygonal epithelial cells having hyperchromatic nuclei associated with extensively necrotic and hemorrhagic areas (Fig. 2b, c).
Fundus fluorescein angiogram (FFA) of left eye revealed delayed filling of peripheral vessels, late staining of vessels and optic nerve head together with some capillary non-perfusion areas and blocked fluorescence in hemorrhagic areas (Fig. 2).
MRI may also discriminate between cystic and hemorrhagic areas with T1 or T2* sequences, information that may be relevant for evaluating the therapeutic challenges for SCT [18, 23] and some intracranial tumors.
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