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These results support a high correlation at the hemisphere level and suggest that the global interhemispheric circulation of epidemics follows an irregular pathway with recurrent changes in the leading hemisphere.
Specifically, we found that the structural asymmetries of the insula – as measured by the extent of its surface, but also by its volume – are strongly related to functional asymmetries in the supramarginal gyrus, a structure typically associated with the control of gesture, as well as to functional asymmetries measured at the whole hemisphere level.
We are talking about the Human Brain Project, Markram's audacious plan to build a working model of the human brain – from neuron to hemisphere level – and simulate it on a supercomputer within the next 10 years.
Yet, there was still a significant correlation between LIs as measured in the SMG and at the whole hemisphere level (r13 = 0.86, P = 0.000047).
Specifically, insular volume asymmetries correlated significantly with the laterality of activity for gesture assessed both in SMG (r25 = 0.45, P = 0.018) and at the whole hemisphere level (r25 = 0.40, P = 0.036).
The surface asymmetries of the planum temporale, by contrast, did not correlate either with gesture measured in the SMG (r13 = 0.03, P = 0.92) and at the hemispheric level (r13 = −0.10, P = 0.72) or with language assessed in Broca's area (r13 = −0.2, P = 0.47) and at the whole hemisphere level (r13 = −0.24, P = 0.39).
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