It is obviously that correct binding mode prediction can greatly help the binding residues prediction, especially in difficult case.
On the other hand, IL-6 may also indirectly help the binding of CRP to phospholipides on tumour cells, activating the complement system and acting as an opsonin, augmenting tumour cell phagocytosis (Black et al, 2004).
These results suggest that RPA can be extracted more efficiently in high NaCl, and/or that the dissociation of interacting proteins and DNA by high NaCl and possibly secondary conformational changes help the binding of anti-RPA antibodies in autoimmune sera.
Our results appear to corroborate this hypothesis, as the observed EX1-type kinetics indicate that this part of the C-terminal domain of KDM4C possesses unusual conformational flexibility, which in turn could help facilitate the binding of other histone substrates than tri- and dimethylated H3K9.
Soap helps the process by binding with the particles of stain-causing debris after the lemon lifts those particles from the surface of the nail.
P-TEFb has affinity for 7SK and HIV TAR RNA [37], [48] and it is possible that this helps stabilize the binding of HEXIM1 to 7SK in the presence of P-TEFb.
This motif helps in the binding of the MAGUK with the C-terminus of proteins that have the consensus E (S/T) × (V/l) motif [ 19].
A number of reactive intermediates like BP-4,5-oxide and 9-hydroxy-BP-4,5-oxide are formed by BP with this activating system that helps in the binding of BP to bacterial DNA [ 34].
This approach, called competitive binding, helps the device avoid false positives.
