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Simulation of virtual knockouts of genes in these networks is helpful in inferring essentiality [ 23- 26].
The data obtained from RNA-seq projects are also helpful in inferring the basic biological, molecular, and cellular processes [ 19, 20].
Although only the lower-layer cluster loadings (defined later) were used in the association testing and the upper-layer clusters appeared irrelevant, they are indeed helpful in inferring both ancestral allele frequencies and loading matrix through enforcing structure on lower-layer clusters.
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In inferring individual ancestry from genetic data, it is helpful to know the genetic profile of the putative ancestral populations, for example, the allele frequencies determined from samples that represent the progenitors of the admixed individuals.
Benefit from the integration of the large STITCH database, ChemDIS is expected to be helpful for inferring potential diseases associated with poorly characterized chemicals.
Large, multi-locus studies of patterns of genetic diversity have proven helpful for inferring the demographic histories of Drosophila [2] and humans [3], but, apart from Arabidopsis thaliana [4] and domesticated crops [5], such studies remain rare in plants.
This level of bioinformatic characterization is helpful for inferring functional similarities between proteins and will strengthen the evidence for the involvement of the candidate gene in initiation or execution of apoptosis in protozoans.
Thus, interactions between protein groups that share motifs are likely to be helpful for inferring kinase-substrate interaction networks.
Therefore, we can conclude that having temporal profiles with various types of stimuli is more helpful for inferring networks than having replicated temporal profiles with a single stimulation.
The proper identification of true orthology relationships is often helpful for inferring gene function and translating knowledge between model organisms and more complex species.
In particular, cost benefit analysis of climbing plant behaviour should be helpful to infer the selective pressures that have operated to shape current climber ecological communities.
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