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The SPIRIT 2013 Explanation and Elaboration paper, together with the Statement, should help with the drafting of trial protocols.
Dr. Albert Crenshaw, Centre for Musculoskeletal Research, University of Gävle, for language support and help with the drafting of the paper and Peter Hägglöf for technical assistance regarding the western blot analysis.
WMB coordinated and helped with the draft of the manuscript.
SAHR helped with the draft of manus and contributed patients.
AG participated in the coordination of the study and helped with the draft of the manuscript.
WM participated in the design of the study and helped with the draft of the manuscript.
Angel Lanas designed the study and helped with the draft of the manuscript.
DH participated in the clinical follow-up and helped with the draft of the manuscript.
JH performed the phenotypic and molecular identification and helped with the draft of the manuscript.
HVH, performed the statistical analysis, helped with the draft of the manuscript.
TE helped with the draft of the manuscript and interpretation of the results.
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